Set in a future where society collapses following a catastrophic pandemic, Die Alone follows Ethan (Douglas Smith), a young man with amnesia, who bands together with Mae (Moss), a rugged survivalist. Under siege from the zombie-like monsters created by the outbreak, Ethan must use Mae’s survival skills to find his missing girlfriend, before a fateful encounter with Kai (Grillo) unravels a secret that lies just beyond his fractured memory.